VAID'S ICS – Best UPSC Anthropology Coaching in Delhi Since 1985

Comprehensive Classroom Course · Admissions openRegister now
Home/Anthropology/Mains PYQ/2026/Paper I/Human Genetics & Human Biology
UPSC MainsAnthropology Optional Paper I 2026 10 Marks Model Answer Available

Genetic Polymorphism and Natural Selection — 2026 Paper I

Question · 2026 · Paper I · 10 Marks

Genetic polymorphism and natural selection.

Model Answer

VAID ICS
Approach

  • Demand of Question: Define genetic polymorphism and explain how natural selection may reduce or maintain genetic variation.
  • Structuring the Response: Definition → transient vs balanced polymorphism → HbA/HbS–malaria example → other evolutionary forces → conclusion.
  • Key Dimensions to Cover: Haldane, heterozygote advantage, directional selection, balancing selection, malaria, gene–culture interaction.

 

Model Answer

Introduction: Genetic polymorphism is the occurrence of two or more inherited variants at a locus in an interbreeding population at appreciable frequencies, too high to be explained simply by recurrent mutation. Its frequency pattern reflects selection as well as drift, gene flow and demographic history.

Natural selection influences polymorphism in two broad ways.

  1. Transient polymorphism: Under directional selection, one allele has higher fitness in a particular environment and progressively rises in frequency; variation may therefore decline over time.
  2. Balanced polymorphism: Selection can maintain two or more alleles when their fitness advantages differ among genotypes or environments. The classic human example is the HbA/HbS system in malaria-endemic regions, anticipated in J. B. S. Haldane’s discussion of malaria and haemoglobin variants. But it is A C Allison 1954 demonstrated that , HbS causes sickle-cell disease, while HbA lacks the malaria-related protection associated with HbS. HbS heterozygotes obtain substantial protection against severe falciparum malaria while usually avoiding severe sickling disease. This heterozygote advantage maintains both alleles in the population.

Other examples include malaria-related selection involving some G6PD variants. Gene–culture change can also create new selective environments, as dairying did for lactase persistence.

Conclusion: Natural selection does not invariably eliminate genetic variation; under particular ecological conditions it can actively maintain adaptive polymorphism in human populations.

Want feedback on your answer?

Join the Anthropology workshop or get structured answer-writing guidance from VAID ICS.

UPSC Anthropology Optional 2026 — Paper I

28 questions
Syllabus: Paper I > Applications of Anthropology > Ergonomics > Anthropometry
2026Paper IApplied & Forensic AnthropologyModel answer available
Syllabus: Paper I > Human Growth and Development > Growth patterns > Canalization and catch-up growth
2026Paper IHuman Genetics & Human BiologyModel answer available
Syllabus: Paper I > Family > Contemporary trends > Feminist movement and family
2026Paper IMarriage & FamilyModel answer available
Syllabus: Paper I > Applications of Anthropology > Medical Anthropology > Culture and health
2026Paper IApplied & Forensic AnthropologyModel answer available
Syllabus: Paper I > Religion, Myth and Ritual > Myth > Myth as oral literature
2026Paper IAnthropology of ReligionModel answer available
Syllabus: Paper I > Archaeological Anthropology > Dating methods > Thermoluminescence
2026Paper IPrehistoric ArchaeologyModel answer available